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Division of Signaling and Gene Expression at the La Jolla Institute for Immunology

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Category: Research

Strange DNA structures may drive cancer development

December 22, 2021April 29, 2022Research

December 22, 2021 LA JOLLA, CA—Scientists at the La Jolla Institute for Immunology (LJI) have uncovered how loss of TET enzymes can lead to B cell lymphoma. Their research, published in Nature Immunology, could potentially open opportunities for designing drug treatment […]

Immune cells can detect cancer

October 20, 2021April 29, 2022Research

LA JOLLA – Living with an immune system is like carrying a tool belt. Your body can whip out specialized immune cells if you encounter a virus, eat rotten food, or get a paper cut. The immune system is equipped […]

Preparing T cells for the long haul

July 19, 2021April 29, 2022Research

LA JOLLA—Fighting a tumor is a marathon, not a sprint. For cancer-fighting T cells, the race is sometimes just too long, and the T cells quit fighting. Researchers even have a name for this phenomenon: T cell exhaustion. In a […]

Hard-working enzyme keeps immune cells in line

June 25, 2021April 29, 2022Research

LA JOLLA, CA—Researchers at La Jolla Institute for Immunology (LJI) have shed light on a process in immune cells that may explain why some people develop cardiovascular diseases. Their research, published recently in Genome Biology, shows the key role that TET enzymes play […]

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