Division of Signaling and Gene Expression at the La Jolla Institute for Immunology
LA JOLLA, CA— March 14, 2017 One reason we survive into adulthood is that cell-killing T cells usually recognize and eliminate cancerous or pathogen-infected cells. But prolonged overactivity of immune cells summoned to a tumor or infection site can render […]
LA JOLLA, CA— December 19, 2016 In a bid to better understand the gene expression patterns that control T cell activity, researchers at the La Jolla Institute for Allergy and Immunology mapped genome-wide changes in chromatin accessibility as T cells […]
LJI investigators report how loss of TET tumor suppressors halts T cell maturation and promotes aberrant proliferation LA JOLLA, CA—December 12, 2016 Members of the TET family of proteins help protect against cancer by regulating the chemical state of DNA […]
LA JOLLA, CA— December 7, 2016 The fate of stem cells is determined by series of choices that sequentially narrow their available options until stem cells’ offspring have found their station and purpose in the body. Their decisions are guided […]
