LA JOLLA, CA— December 19, 2016 In a bid to better understand the gene expression patterns that control T cell activity, researchers at the La Jolla Institute for Allergy and Immunology mapped genome-wide changes in chromatin accessibility as T cells […]

LJI investigators report how loss of TET tumor suppressors halts T cell maturation and promotes aberrant proliferation LA JOLLA, CA—December 12, 2016 Members of the TET family of proteins help protect against cancer by regulating the chemical state of DNA […]

LA JOLLA, CA— December 7, 2016 The fate of stem cells is determined by series of choices that sequentially narrow their available options until stem cells’ offspring have found their station and purpose in the body. Their decisions are guided […]

LJI researchers show that TET-loss of function causes rapid development of malignant cancer La Jolla, CA – December 9, 2015 Members of the TET (short for ten-eleven translocation) family have been known to function as tumor suppressors for many years, […]